Education 

 

Doctor of Philosophy, Biochemistry/Molecular Biology

    Massachusetts Institute of Technology    2001 

 

Coursework in New Enterprise and Entrepreneurial Strategy

    MIT - Sloan School of Management    1998-1999 

 

Bacholor of Science, Mircobiology

    University of Michigan    1995

 

 

Previous Work Experience

 

Georgia Tech Research Institute

    Senior Research Scientist, Electro-Optical Systems 

    Laboratory    2007-Present

 

Georgia Institute of Technology

    Assistant Professor, School of Biology    2007-Present

 

University of Michigan Medical School

    Research Assistant Professor, Bioinformatics Program   

    2006-2007

    Co-Director, NLAID/University of Michigan Biodefense

    Proteomics Research Center

    Research Investigator, Bioinformatics Program    2003-2006



Registrations, Professional Affiliations, and Special Honors

 

American Lung Association Postdoctural Research Fellowship (declined), 2002

Pharmaceutical Research and Manufacturers of America Foundation Postdoctoral Fellowship in Bioinformatics, 2001

High Honors in Thesis Research, University of Michigan, 1995

Dean’s List, University of Michigan, 1992-1995



Committee Memberships

Georgia Tech School of Biology MS in Bioinformatics Program Steering Committee    2008-Present

Georgia Tech School of Biology Faculty Search Committee    2007-2008

Proposal Reviewer, University of Michigan Medical School Center for Computational Medicine and Biology Pilot Grant Program    2006

Abstract Review Committee, 3rd Great Lakes Bioinformatics Retreat, Aug. 16-17, 2004    2004

Interoperability Working Group, NIH/NIAID Biodefense Proteomics Research Centers (Responsible for developing guidelines and database structures for PRC data storage and dissemination)    2004-Present

 

 

 

Patents

 

“Live Attenuated Anthrax Vaccines” US Provisional Patent Application filed August 2, 2006 (US Patent and Trademark Office serial number 60/834,860).

 

Major Reports and Publications

 

Peer-reviewed publications
C. E. Bogden, D. Fass, N. Bergman, M. Nichols, and J. M. Berger. (1999). "The Structural Basis for Terminator Recognition by the Rho Transcription Termination Factor." Molecular Cell 3, 487-93.

N. H. Bergman, W. Johnston, and D. P. Bartel. (2000). "Kinetic Framework for Ligation by an Efficient RNA Ligase Ribozyme." Biochemistry 39(11): 3115-23.

M. E. Glasner, N. H. Bergman, D. P. Bartel. (2002). "Metal dependence of the Class I RNA Ligase Ribozyme." Biochemistry 41(25): 8103-8112.

N. H. Bergman and B. J. Akerley. (2003). “Position-based Scanning for Comparative Genomics and Identification of new Genetic Islands within the H. influenzae type b Genome.” Infection and Immunity 71(3): 1098-1108.

N. H. Bergman, N. C. Lau, V. Lehnert, E. Westhof, D. P. Bartel. (2004). "The Three-Dimensional Architecture of the Class I Ligase Ribozyme." RNA 10(2): 176-184.

H. Liu#, N. H. Bergman#, B. Thomason#, S. Shallom, A. Hazen, J. Crossno, D. A. Rasko, J. Ravel, T. D. Read, S. N. Peterson, J. Yates, III and P. C. Hanna. (2004). “Formation and Composition of the Bacillus anthracis Endospore.” Journal of Bacteriology 186(1):164-178. (#equal contribution)

N. H. Bergman, K. D. Cesarek, R. Gaspard, L. M. Shetron-Rama, J. Quackenbush, and P. C. Hanna. (2005). “Murine Macrophage Transcriptional Responses to Bacillus anthracis infection and intoxication.” Infection and Immunity, 73(2):1069-1080.

N. Fisher, L. Shetron-Rama, A. Herring, B. Heffernan, N. H. Bergman, and P. C. Hanna. (2006) “The dltABCD Operon of Bacillus anthracis Sterne 34F2 is Expressed During Outgrowth and is Required for Virulence and Resistance to Peptide, Enzymatic, and Cellular Mediators of Innate Immunity.” Journal of Bacteriology 188(4):1301-1309.

K. D. Passalacqua, N. H. Bergman, A. Herring, and P. C. Hanna. (2006) “The Superoxide Dismutases of Bacillus anthracis Do Not Cooperatively Protect Against Endogenous Superoxide Stress.” Journal of Bacteriology, 188(11):3837-3848.

N. H. Bergman*, E. C. Anderson, E. E. Swenson, M. M. Niemeyer, A. D. Miyoshi, and P. C. Hanna. (2006) “Transcriptional Profiling of the Bacillus anthracis Life Cycle in vitro and an implied model for regulation of spore formation” Journal of Bacteriology, 188(17):6092-6100. (*corresponding author)

N. H. Bergman*, K. D. Passalacqua, P. C. Hanna, and Z. S. Qin. (2007) “Operon Prediction in Sequenced Bacterial Genomes Without Experimental Information.” Applied and Environmental Microbiology. 73(3):846-54. (*corresponding author)

J. Y. Lee, B. K. Janes, K. D. Passalacqua, B. Pfleger, N. H. Bergman, H. Liu, K. Hakansson, R. V. Somu, C. Aldrich, S. Cendrowski, P. C. Hanna, and D. Sherman. (2007) “Biosynthetic Analysis of the Petrobactin Siderophore Pathway from Bacillus anthracis.” Journal of Bacteriology. 189(5):1698-1710.

K. D. Passalacqua, N. H. Bergman, J. Y. Lee and P.C. Hanna. (2007) “The global transcriptional responses of Bacillus anthracis Sterne 34F2 and sodA1 to paraquat reveal metal ion homeostasis imbalances during endogenous superoxide stress.” Journal of Bacteriology. 189(11):3996-4013.

N. H. Bergman*, E. C. Anderson, E. E. Swenson, B. K. Janes, N. Fisher, M. Niemeyer, A Miyoshi, and P. C. Hanna. (2007) ”Transcriptional profiling of Bacillus anthracis during infection of host macrophages.” Infection and Immunity. 75(7):3434-3444. (*corresponding author)

B. Pfleger, T. Nusca, Y. Kim, J. Lee, C. Rath, J. Scaglione, B. Janes, N. H. Bergman, P. Hanna, A. Joachimiak, and D. Sherman. (2008) “Structural and Functional Analysis of AsbF: Origin of the Stealth 3, 4-Dihydroxybenzoic Acid Subunit for Petrobactin Biosynthesis in Bacillus anthracis.” Proc. Natl. Acad. Sci., 105(44):17133-138.

B. Ondov, A. Varadarajan, K.D. Passalacqua, and N. H. Bergman*. “Efficient mapping of Applied Biosystems SOLiD sequence data to a reference genome for functional genomics applications.” Bioinformatics 24(23):2776-7. (*corresponding author)

 

Books

N. H. Bergman, (Editor) Comparative Genomics, vols. 1 and 2 (Methods in Molecular Biology Series volumes 395 and 396). Totowa, NJ, USA. Humana Press. November, 2007.

N. H. Bergman, (Editor) Microbial Systems Biology—New Directions and New Opportunities. John Wiley & Sons, Oxford, UK. (to be published in 2009).

N. H. Bergman, (Editor) Bacillus anthracis and Anthrax. John Wiley & Sons, Oxford, UK. (to be published in 2009).